IVD Test Reagent/Kits, Molecular Assay, Gene Anomaly, Mutation, MAPT
Definition : Molecular assay reagents intended to identify mutations in the microtubule-associated protein tau (MAPT) gene, located at chromosome 17q21.1, which encodes for the microtubule-associated protein tau (MAPT). The MAPT transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. Mutations at this locus have been identifed in patients with a variety of frontotemporal dementias.
Entry Terms : "Frontotemporal Dementia with Parkinsonism Type 17 (FTDP-17) Gene Mutation Reagents" , "Frontotemporal Dementia with Pakinsonism Gene Mutation Reagents" , "MAPT Gene Mutation Detection Reagents" , "Reagents, Molecular Assay, Gene Anomaly, Mutation, MAPT"
UMDC code : 24599