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Hemodialysis Units, Renal, Continuous Replacement Therapy

Definition : Hemodialysis units designed for the continuous replacement of the main activity of the kidneys by removing water and wastes at a slow and steady rate (i.e., continuous renal replacement therapy [CRRT] machines). Blood is removed via an extracorporeal circuit, using either arteriovenous access (typically femoral artery to femoral vein) or a venous-venous access (e.g., jugular, femoral, subclavian vein), passed through an extracorporeal dialyzer that allows the transfer of substances usually by diffusion to decrease biochemical abnormalities as well as fluid, electrolyte, and acid-base imbalances; and returned to the patient (i.e., a hemodialysis procedure). These units frequently have capabilities to perform other procedures, such as filtration and fluid replacement (usually calcium and lactate) by convection (hemofiltration) and a combination of hemodialysis and fluid replacement by diffusion and convection (hemodiafiltration). CRRT unit's main components are usually a dialysate-delivery system that delivers the previously prepared dialysate solution from a bag to the dialyzer, the extracorporeal blood-delivery circuit that slowly circulates a portion of the patient's blood through the dialyzer and returns to the patient, a disposable dialyzer with specialized membrane filters in which solute exchange takes place, and devices to perform fluid replacement. Each component has its own monitoring and control circuits. Continuous renal replacement units are intended for temporary continuous partial replacement of renal functions in hemodynamically unstable patients with acute renal failure and excess urea in blood (i.e., uremia, also known as azotemia) and/or fluid overload; they are also used for the treatment of other critical diseases, such as refractory pulmonary edema, pericarditis, hypothermia, or poisonings with a dialyzable toxin.

Entry Terms : "Hemodialysis Units, Continuous Replacement Therapy" , "Continuous Renal Replacement Therapy Units" , "CRRT Units"

UMDC code : 23426

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Edwards Lifesciences Corp

Company Type: Parent

Edwards Lifesciences is the global leader in the science of heart valves and hemodynamic monitoring. Driven by a passion to help patients, the company partners with clinicians to develop innovative technologies in the areas of structural heart disease and critical care monitoring that enable them to save and enhance lives.

NxStage Medical Inc

Company Type: Parent

NxStage is more than just a company; we are leading the renal revolution. By our own design, we're at the leading edge of a movement to transform renal care. To make it simpler. To make it portable. To expand treatment options for clinicians by overcoming traditional barriers. To enhancepatient freedom and fulfillment.

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