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IVD Test Reagent/Kits, Immunocytochemistry/Immunohistochemistry, Stain

Definition : Reagents designed for artificial coloration of cells and/or tissues that have been labeled with a primary antibody during immunocytochemistry or immunohistochemistry tests. Typically, these reagents are intended to allow chromogenic or fluorescent detection of antibody binding. Chromogenic detection methods typically use a secondary antibody conjugated to an enzyme (e.g., alkaline phosphatase, horseradish peroxidase). When the enzyme is provided the appropriate substrate (e.g., nitro-blue tetrazolium and 5-bromo-4-chloro-3'-indolyphosphate [BCIP/NBT], diaminobenzidine [DAB]), it will form colored precipitates that stain the cells. Slides stained using chromogenic methods are typically visualized using light microscopy. Fluorescent detection methods typically use a secondary antibody conjugated to a fluorophore (e.g., fluorescein isothiocyanate [FITC], rhodamine) that re-emits light at a specific wavelength when exposed to light. Slides stained with flourophores are typically visualized using fluorescence or confocal microscopy. Simultaneous staining of multiple primary antibodies can be accomplished by appropriate selection of secondary antibodies that are able to discriminate between the used primary antibodies. In the case of chromogenic detection methods, secondary antibodies conjugated to enzymes specific for different substrates and producing different colored pigments are used. In the case of fluorescent methods, secondary antibodies conjugated to fluorophores with non-overlapping excitation and emission spectra are used.

Entry Terms : "Stains, Immunofluorescence" , "Immunocytochemistry Detection Reagents" , "Immunocytochemistry Stain Reagents" , "Immunofluorescence Detection Reagents" , "Immunohistochemistry Detection Reagents" , "Stains, Immunocytochemistry" , "Stains, Immunohistochemistry"

UMDC code : 32974

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1-10 of 10 Match(es).

Andwin Scientific

Company Type: Parent

Electron Microscopy Sciences (EMS)

Company Type: Parent

Electron Microscopy Sciences has been specializing in the manufacturing, preparation, and distribution of only the highest quality chemicals, supplies, and equipment, for microscopy, and all of its related fields.

InBios International Inc

Company Type: Parent

InBios International, Inc. is a medical diagnostic company that specializes in developing, manufacturing and marketing medical diagnostic tests for the detection of infectious diseases. Since its inception in 1996, InBios has developed proprietary technologies useful in the development of rapid and ELISA based immunodiagnostic assays. It has also licensed antigens from major corporations and research organizations from which a number of its assays have been developed.

Newcomer Supply

Company Type: Parent

Poly Scientific R&D Corp

Company Type: Parent

Polysciences Inc

Company Type: Parent

The company was founded in 1961 to provide sample preparation products for electron microscopy as nano-scale samples were starting to reveal new knowledge. Embedding products were added for histology (the study of tissue) applications soon after, enabling tissue embedment in plastic blocks, in addition to paraffin. Dyes and stains were developed to implement better visualization of the samples. In cooperation with federal agencies, monodisperse polymeric microspheres were developed for diagnostic kit applications.

Rowley Biochemical Inc

Company Type: Parent

ScienCell Research Laboratories

Company Type: Parent

SCIMEDX Corp

Company Type: Parent

SCIMEDX Corporation is a highly flexible company, with over 30 years in the medical diagnostics industry, specializing in IFA, ELISA, and automated laboratory platforms, with a focus on autoimmune diseases. The strength of the organization is the collective diversified experiences of the personnel in many areas of diagnostics and biochemistry.

Statlab Medical Products Inc

Company Type: Parent

Statlab offers a "one stop" source for consumables, kits, and equipment for the anatomic pathology laboratory. An ability and willingness to customize product packaging along with a strong desire to service the customer on their terms has set Statlab apart in the supply arena.

1-10 of 10 Match(es).