Home > Resources > Anti-Thyroglobulin (TG) ELISA Kit

Anti-Thyroglobulin (TG) ELISA Kit

Already a member? Click here to sign in

Step 1: Not registered? Please complete this form to view content

Step 2: Create Your Medical Product Guide Account

Step 3: Create Your Professional Information

* indicates required field

By clicking the button above you agree to our Terms of Use. We take your privacy seriously. For more information please read our Privacy Policy.

Product Literature/Brochure from GenWay Biotech Inc

Thyroglobulin (TG) is a 660 kDa, dimeric glycoprotein produced by the thyroid gland and involved in the storage and synthesis of thyroid hormones. It is the precursor of the thyroid hormones 3,3,5-triiodo-L-thyronine (T3) and L-thyroxine(T4).The enzyme thyroperoxidase (TPO) promotes iodination of tyrosine residues in thyroglobulin molecules, formingmonoiodotyrosine (MIT) and diiodotyrosine (DIT). TPO further catalyzes the intramolecular coupling of two molecules ofdiiodotyrosine to produce tetraiodothyronine (T4). TG autoantibodies are also found in some clinically euthyroid individuals, but usually at lower concentrations than inpatients with clinical disease.In addition to autoimmunity, anti-TG antibodies may develop in patients suffering from thyroid cancer. High levels of anti-TG may interfere with correct determination of serum thyroglobulin. TG is an established tumor marker for thyroid cancer,and is used post-surgically to evaluate the effectiveness of treatment and to monitor for disease recurrence.