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Company : Express Diagnostics Int'l Inc

UMDC Code : 452256

Buprenorphine is a semisynthetic opioid analgesic derived from thebain, a component of opium. It has a longer duration of action than morphine when indicated for the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence. Low dose buprenorphine produces sufficient agonist effect to enable opioid-addicted individuals to discontinue the misuse of opioids without experiencing withdrawal symptoms. Buprenorphine carries a lower risk of abuse, addiction, and side effects compared to full opioid agonists because of the ceiling effect, whereby increased doses of the drug do not produce increased effects after a certain point, or ceiling. However, it has also been shown that buprenorphine has abuse potential and may itself cause dependency. Subutex, and a buprenorphine/Naloxone combination product, Suboxone, are the only two forms of buprenorphine that have been approved by FDA in 2002 for use in opioid addiction treatment. Buprenorphine was rescheduled from Schedule V to Schedule III drug just before FDA approval of Suboxone and Subutex.

Product URL : http://www.drugcheck.com/dc_info-bup.html

Last Updated : 03/16/2013

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