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Anti-Cardiolipin (Phospholipids) Syndrome

Company : Innominata dba GenBio

UMDC Code : 405964

Anti-cardiolipin (aCL) autoimmune antibodies are a subset of antibodies which react with negatively charged phospholipids. Anti-cardiolipin antibodies are frequently observed in patients with SLE. One autoantibody, LA, is measured with a bioassay and the other autoantibody, aCL, is measured based on affinity for cardiolipin. In many cases both autoantibodies are present in a single patient and may be the same antibody in some cases. During the 1990s the complex interaction of a common serum protein, beta-2 glycoprotein, and a fatty acid, phosphotydl serine, was defined and shown to be a specific and diagnostic antibody response. Kits designed before the 1990s did not reliably detect anti-beta-2 glycoprotein, the most significant disease specific component. GenBios kits not only detects this important beta-2 glycoprotein reaction, but assures its reproducible and sensitive measurement by standardizing the phosphotydl serine concentration.

Product URL : http://www.genbio.com/products.php?product=anticar

Last Updated : 03/16/2013

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