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Creatine Kinase (CK) is primarily found in striated muscle,
brain and heart tissues. The determination of CK activity in
plasma or serum, provides a sensitive marker for the
detection of skeletal muscle disease. e.g. In Duchenne
type muscular dystrophy levels of CK up to 50 times the
upper limit of normal may be encountered. In progressive
muscular dystrophy enzyme activity in serum is highest in
infancy and childhood.
CK activity is also useful in diagnosis of myocardial
infarction and cerebrovascular accidents.
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Company:
Date:
December 02, 2008
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PRINCIPLE(3) Immunoinhibition Assay: An antibody is incorporated in the
CK reagent. This antibody will bind to and inhibit the activity
of the M subunit of CK-MB. This means that only the activity
of the B subunit in serum is measured. If the activity is
multiplied by a factor of 2, it will give the activity of CK-MB
in serum.
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Company:
Date:
December 02, 2008
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Creatine kinase (CK) catalyzes the reversible reaction of creatine and ATP to from creatine phosphate and ADP which plays very important role in the function of energy storage in the human tissue. It presents mostly in skeletal muscle, heart and brain. Damage of muscle and heart tissues will release of CK to the blood stream and result in the increase of CK activity. Determination of CK activity in serum or plasma is a good diagnosis of muscular dystrophy and other skeletal muscle disease myocardial infarction, renal damage and dysfunction.
CK catalyzes the conversion of creatine phosphate and
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Company:
Date:
December 02, 2008
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An established marker for diagnosis of MI. Raised 4- 6hours after event, peak at 18-24 hours, back to baseLate marker level in 3-4 days.
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Company:
Date:
December 02, 2008
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Creatine kinase (CK) is an enzyme which is found primarily in skeletal muscle, cardiac muscle and brain tissue. Elevated levels of CK are associated with myocardial infarction, various muscle disorders and diseases such as progressive Duchenne-type muscular dystrophy. In myocardial infarction, peak CK levels occur 24 to 36 hours after onset of chest pain and depending on the extent of damage can reach more than 10 times normal levels.
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Company:
Date:
December 02, 2008
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Creatine Kinase (CK) plays an important role in the energy-storing
mechanism of tissue by catalyzing the reversible reaction between
creatine and ATP to form creatine phosphate and ADP. CK is
distributed in various organs; the highest activities (in decreasing
order) are skeletal muscle, heart, and brain.1 Thus, determination of
CK is an aid in diagnosing muscular dystrophy and other diseases of
the skeletal muscles, myocardial infarction, hypothyroidism, renal
diseases, and/or dysfunction.2
The early procedure for determining CK was based on the rate of
ATP formation.3 A modified method was d
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Company:
Date:
December 02, 2008
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CREATINE KINASE (CK-NAC) STABLE LIQUID
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Company:
Date:
December 02, 2008
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CREATINE KINASE-MB (CK-MB) FREEZE DRIED
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Company:
Date:
December 02, 2008
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Creatine kinases are dimeric molecules composed of M and B subunits
and exist as the isoenzymes MM, MB, and BB.1 The subunits M and B
are immunologically distinct; CK-MM and CK-MB are distributed
primarily in the skeletal muscle and heart muscle, respectively. While
CK-BB is present mainly in the brain and in tissues composed of smooth
muscle.2 Following acute myocardial infarction, CK-MB activity
increases significantly and this elevation is highly specific for the
laboratory diagnosis of myocardial infarction.3,4 Although total CK
activity usually increases following myocardial infarction, i
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Company:
Date:
December 02, 2008
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For the quantitative in vitro determination of Creatine Kinase in serum or plasma. This product is suitable for Manual use.
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Company:
Date:
March 03, 2009
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