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Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products.
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January 03, 2009
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IGF-BP3
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Date:
January 03, 2009
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All current existing IGFBP-3 immunoassays use the binding of specific anti-IGFBP-3 antibodies for signal generation and thus IGFBP-3 quantification. The failure of differentiation between complete IGFBP-3 molecules and their respective fragments (derived physiologically due to the different proteases activities) can lead to erroneous results.
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January 03, 2009
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Insulin-like growth factors (IGF)-I and -II are bound to specific binding proteins (IGFBPs) in the circulation. To date, at least six binding proteins can be distinguished on the basis of their amino acid sequence. They are designated as IGFBP-1, IGFBP-2, ... IGPBP-6 (1). Lately the discovery of a new IGFBP-7 has been discussed (2). The predominating IGFBP in blood is IGFBP-3 which largely determines the total IGF-I and IGF-II concentration. In contrast to the other binding proteins, IGFBP-3 has the unique property to associate with an acid-labile nonbinding subunit (ALS) after binding of eith
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Date:
January 03, 2009
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For determination of serum IGFBP-3 levels. For Research Use Only. IGFBP-3 is found in human serum and has two forms of approximate molecular mass 40 and 43 kDa. IGFBP-3 binds IGF-1 and IGF-2 with similar high affinity. In the blood stream, approximately 90 of IGFBP-3 is found in a ternary complex of 140 kDa. This complex comprises an acid-labile subunit (α-subunit), IGFBP-3 (β-subunit) and IGF-1 or IGF-2. This binding prolongs the metabolic half-life of IGF-1 in the circulation and serves as a metabolic reservoir of IGF-1. Due to stable circadian levels, a single IGFBP-3 measurement proved to
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Company:
Date:
January 03, 2009
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Insulin-like growth factors (IGF)-I and -II are bound to specific binding proteins (IGFBPs) in the circulation. To date, at least six binding proteins can be distinguished on the basis of their amino acid sequence. They are designated as IGFBP-1, IGFBP-2, ... IGPBP-6 (1). Lately the discovery of a new IGFBP-7 has been discussed (2).
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Company:
Date:
January 03, 2009
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Insulin-like growth factors (IGF)-I and -II are bound to specific binding proteins (IGFBPs) in the circulation. To date, at least six binding proteins can be distinguished on the basis of their amino acid sequence. They are designated as IGFBP-1, IGFBP-2, ... IGPBP-6 (1). Lately the discovery of a new IGFBP-7 has been discussed (2). The predominating IGFBP in blood is IGFBP-3 which largely determines the total IGF-I and IGF-II concentration. In contrast to the other binding proteins, IGFBP-3 has the unique property to associate with an acid-labile non-binding subunit (ALS) after binding of eit
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Company:
Date:
January 03, 2009
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Insulin-like growth factors (IGF)-I and -II are bound to specific binding proteins (IGFBPs) in the circulation. To date, at least six binding proteins can be distinguished on the basis of their amino acid sequence. They are designated as IGFBP-1, IGFBP-2, ... IGPBP-6 (1). Lately the discovery of a new IGFBP-7 has been discussed (2).
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Company:
Date:
January 03, 2009
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IGF-BP3
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Company:
Date:
January 03, 2009
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IGF-BP5
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Company:
Date:
January 03, 2009
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